Viagra helps in toning up of the heart
May 21, 2008
TORONTO: Muscular dystrophy is a common symptom in almost all kind of muscle wasting diseases. As the time passes on face, arm, leg, spine and heart muscles deteriorate and wither away.
Sildenafil citrate or more commonly known as Viagra is identified to slow down the breakdown of cyclic GMP, an enzyme that not only dilates the blood vessels in the penis, but is also concerned in the indicating pathways that keep the heart healthy and in proper shape.
A group of researchers led by Christine Des Rosiers at the Montreal Heart Institute, Canada, manageed an adrenaline like matter in mice that had been engineered to develop texture of human MD.
Des Rosiers found that mice given a dose of Viagra equivalent to the amount a man would get for erectile dysfunction (ED) deal considerably better than animals not given the drug. Echocardiography and other measures demonstrated that the heart function was better, signifying that Viagra had secluded the heart muscle, the New Scientist online said “It makes perfect sense that it would work in these mouse models,” says Elizabeth McNally, at the University of Chicago Medical Center, Illinois. “It fits.”
Though, she concerned that the achievement does not mean a drug for humans is just around the corner it is hard to run clinical trials in patients with muscular dystrophy, since their numbers are small.
ANI
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