Early skin cancer can be caught by Gene screening
May 19, 2008
London - The consequences of 3 researches proposes that gene screening may help detect persons who are most probable to contract skin cancer after sitting in the sun.
While studying patients with melanoma and other types of skin cancer, studies in Iceland and Australia recognized a gene connected to a person’s skin tone as well as his/her chances of receiving skin cancer.
Kari Stefannson, CEO of DeCODE Genetics at Reykjavik, said that a mutation in a gene called ASIP doubles the risk of melanoma in sun-starved Icelanders.
The studies also researched the genomes of tens of thousands of blondes, redheads, cancer patients and healthy people from Iceland, Sweden and Eastern Europe with a sight to determining additional genes that affect skin color and cancer.
They experiential that 2 mutations in the gene ASIP were firmly linked to red hair, freckles and sun sensitivity.
“In Iceland you can avoid sunlight because it is so rare,” New Scientist quoted Stefannson as saying.
Stuart MacGregor, a geneticist at Brisbane-based Queensland Institute of Medical Research in Australia, approved: “It doesn’t look like its just pigmentation.”
“Looking at just skin color will only take you so far,” he added.
Jonathan Rees, a skin cancer expert at the University of Edinburgh in Scotland added that any gene affecting complexion was almost sure to play a role in skin cancer, as well.
“It is an open question whether genes will provide better markers of danger than good measures of skin color. I am a sceptic,” he said.
An investigated article on the new findings has been available in the journal Nature Genetics. (ANI)
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