Carbon monoxide might help heart patients- Research
May 27, 2008
Washington - Carbon monoxide (CO) is being known for its hazardous effects. But in the recent studies it has been suggested that in spite of its harmful effects CO is beneficial for patients experiencing cardiopulmonary bypass (CPB) surgery.The investigation headed by Torsten Loop has found that car exhaust (or CO) may encourage cell endurance and decrease lung inflammation in cardiopulmonary bypass or CPB patients.
Almost 2 % of patients suffering from cardiac surgery suffer from serious lung injuries and mortality rates for these patients can surpass 60 %.
“Cardiac surgery is one of the most severe situations a patient can face,” said Dr. Loop.
“Although a heart-lung machine ensures that organs are supplied with blood, and therefore oxygen, the nature of heart surgery means that normal operation of the lungs is impaired - potentially resulting in lung injury.
“Our findings support that inhaled CO provides anti-inflammatory effects in the lungs and decreases the instance of cell death during CPB.
“Additionally, and of greater importance, these effects occurred when CO was administered as a pre-treatment - with the advantage of short exposure time, which limits how avidly CO can bind to hemoglobin,” Loop also added.
Dr John G. Laffey, of the Clinical Sciences Institute, National University of Ireland said that “the study might open new avenues”.
“A fascinating aspect of this study is that pre-treatment with CO before CPB was effective in protecting the lung,” said Dr. Laffey.
“These findings may support evidence that CO can trigger the body into a state that helps to protect it against the sometimes damaging effects of CPB” Dr. Laffey also added.
(ANI)
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