Sickle Cell Anemia
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Facts to Know about Sickle cell Anemia

“Sickle Cell Anemia” is a disease in which the blood cells are affected. It is a genetic disorder that can be inherited. In this disease, the blood cells take an abnormal shape and sometimes it takes the shape of a sickle. In normal condition, blood cells possess flexibility but when this disease affects these cells, blood cells begin to lose its flexibility and start to take the form of a sickle. Inadequate supply of Oxygen in some tissues is one of the major features of this disease. The symptoms of this disease can last throughout the entire life of a person. If a person is suffering from chronic Sickle cell Anaemia, the symptoms of this disease may occur sporadically and this can deter a patient from leading a normal life. It has been observed that, the average life expectancy reduces to forty-two years in males and forty-eight years in females if they are affected by this disease.

Though this disease can affect any person of any age group, people who are residing in Sub-Saharan Africa are more susceptible to this disease.

Sickle Cell Anemia Causes

Every body inherits two copies of haemoglobin gene from his/her parents. It has been observed that people, who suffer form Sickle Cell Anaemia, possess two HbS genes. If a person possesses one HbS gene and one HbA gene, he is vulnerable to this disease. Actually, this disease is an autosomal recessive genetic condition that may lead to many complications.

Inheritance is potent cause of this disease. If one parent is affected by sickle-cell anemia and another is bearing the traits of it, there is a 50% chance that this disease can affect their children. If both the parents are bearing the traits of Sickle Cell Anaemia, there is 25% chance that their children will inherit this disease.

Sickle Cell Anemia Symptoms:

One can experience severe pains in some organs of his body due to lack of oxygen supply in the tissues. Sometimes organs can be damaged by it. This kind of symptoms generally emerges when a person is suffering from exhaustion, dehydration or another ailment. Heart, liver, spleen and kidney are some of the vital organs of the body that can be damaged by this disease. One can experience acute pain in bones. This is also another prominent cause of Sickle Cell anaemia. Anaemia is certainly the potent sign of this disease.

Sometimes, the symptoms of this disease may appear sporadically and may bring some lethal complications. One can suffer from cerebral hemorrhage or cerebral infarction. A patient may have to suffer from cholecystitis and Cholelithiasi. These two are caused by the excessive production of bilirubin. This disease can affect spleen and penis as well. The spleen stops functioning properly and the penis can suffer from infarction. In some cases, bone marrow and bone can be infected by bacteria. This is one of the severe symptoms of this disease. Retinal detachments, vitreous hemorrhages, background retinopathy etc are some of the some of the common diseases of eyes that a patient may have to suffer. Sometimes this can lead to blindness.

Sickle Cell Anemia Treatment:

Though Sickle Cell Anaemia is not a curable disease at all, various treatments are available to reduce the severity of its symptoms. If a patient is suffering from vaso-occlusive crises, painkillers can be applied to relieve him form acute pain. If a person is suffering from inflammation, anti-inflammatory drugs can be applied for generating better result. Naproxen and diclofenac are some of the common anti-inflammatory drugs that are used for this purpose. If a patient is suffering from an itching sensation, Diphenhydramine can be applied for getting better result.

Some antibiotics such as macrolide, quinolone etc can be taken to get relieve from an acute chest crisis. Bone Marrow transplantation can be an effective option that can relieve a patient from the inflammation of bones.


When the symptoms of this disease begin to emerge, a patient should consult with an experienced practitioner in order to stay away from some serious complications of this disease in future.

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