Haemophilia
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Haemophilia is interpreted in clinical terms as a cluster of blood disorders that consist of haemophilia B, haemophilia A and Von Willebrand's disease. These disorders are inherited by a child from his or her parents and the defective gene that causes the disease, stay on the X chromosome. A person suffering from the ailment faces problem with clotting of the blood. His blood can not coagulate as an important clotting element is not found in his system. This factor, results in bleeding for longer than usual.

Types and Causes of Haemophilia

People suffering from Haemophilia-A lacks an important blood clotting element named factor VIII. This element is generally created in the liver of a person. This variant of Haemophilia is more common compared to haemophilia B. The Haemophilia B which is also called Christmas disease stems from the scarcity of factor IX.

In many cases, this does not come from inheritance and the victim acquires the ailment from a newer source. There are dominant and recessive forms of the variant called Von Willebrand's disease. Sometimes natural mutations of genes lead to this syndrome.

As a matter of fact, this is a disease that is seen mostly in the male population. Since the variants of Haemophilia are all X-linked disorders, they find the male population more susceptible as men have just one X chromosome.

Women who inherit the defective gene do not develop the ailment themselves but act as its carrier. They have a high possibility of passing the gene to their offspring. In some rare cases, a woman can inherit two defective X chromosomes from the parents and become afflicted with the ailment.

Symptoms o fHaemophilia

The most prevalent symptoms of the disease are continued bleeding in cases of injury and easy bruising. In some instances, the bleeding can occur without any external reason.

The extremeness of the disease determines the severity of bleeding in a victim. While trivial wounds do not pose much risk in the affected people, internal bleeding can have fatal consequences. If the person suffers from recurring bleeding in his joints, he can develop arthritis later in his life. If any hemorrhage takes place in the brain of the affected person, he has little chances of recovery.

Haemophilia Diagnosis

Antenatal screening and genetic counseling of families having the ailment is a step that can prevent its recurrence in their next generation. People who are acting as the carrier of the faulty genes can be easily detected with blood tests meant for the purpose.

Pregnant ladies can undergo ultrasound tests to evaluate the chance of the disease in the baby. This test also helps to determine the gender of the baby. Thereafter the parents can choose to opt for the advanced tests like CVS and amniocentesis.

Treatment of Haemophilia

As of now, there is no permanent remedy for Haemophilia. However, the patients are given injections containing the lacking clotting element but this can not increase its level in his blood. An important medicine in this context is desmopressin. The children suffering from this disease may require injections on a regular basis.

The clotting factor concentrate was initially derived from donated blood, but nowadays the advancements of medical science have enabled the doctors to procure it artificially. Since this material plays a crucial role in combating bleeding related problems, the affected people should store it within their reach.

They also need to keep information about the location of nearby treatment centers as the clotting factor concentrate is not found in general hospital or health centers. The artificially procured solutions are also known as recombinant factors.

After the advent of the recombinant factors, the earlier risks related with donated blood such as HIV or hepatitis virus, have been largely eliminated. The major concern that haunts the doctor is the chances of vCJD infection. This infection can take place from previous treatments where blood products were employed.

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Comments

thanks for providing a clear information
#1 - kavitha - 04/18/2009 - 04:05
thanx for ur imformation i need some imformation physioterapy management of haemophilia
#2 - dr. atul - 05/15/2009 - 09:29
thanks for giving information I need some more information for what is the vitamins to eat for recover these paitiant.
#3 - V. DAYAL - 06/23/2009 - 05:06
thanks for put this type of information
i have one question
if uncle suffering from haemophilia than there is chace occouring haemophilia in his nephew?
#4 - ramkrishna - 09/24/2009 - 05:28
Can Stem Cell or Gene therapy will be used for Haemophilia, specially for liver to induce it produce FVIII and may be for Haemophilia B also?
#5 - Sanjeev (SanKum) - 10/02/2009 - 03:03
If uncle is suffering from haemophilia then there is chance that his nephew will get affected(son of sister only)if sister of haemophilic is carrier of haemophilia.otherwise no chance
#6 - priya - 06/10/2011 - 08:05
what are the disadvantages/advantages of testing for haemophillia
#7 - hahahahahahahahahaha - 06/15/2011 - 22:37
I am myself a heamophilia patient.I fully know the pain of this disease,when i got swelling in any joint i pray to my God please let me die.Pain of this disease really cruel.Wound is fatal.For more details contact on::09797914227.
#8 - Gulzar.Ah.Pala.From:Kashmir - 06/27/2011 - 13:23
thanx 4 de information. i need the therapeutic doses and its administration information.
#9 - anil - 07/01/2011 - 08:28
i realy thanks god to give me opportunity to give re leaf to patient suffering from some non curable diseases like diabeties, arthritis, thyroid, haemophelia, thalasemia, sickel cell anemia, pcod, cyst etc.

but my condition is this my patient after getting benefit must work for human being like- marriage of poor girls, to help disabled person and children. as per your pocket allow.

[email protected]
9839354290

#10 - MAHESH - 07/14/2011 - 01:57
my two chield are suffering from heamophilia please tell me letest treatment of there now i do please contect me 09414769529, 01429277316
#11 - ram dhan meena - 08/21/2011 - 02:33
Thanx for giving such a great information about haemophilia.My elder brother is suffering from the same disease if anyone have any recent or more information about this please let me know

contact no:9860535541
#12 - poonam - 09/14/2011 - 00:02
i am a haemophilic patient & i know what abnormality means but all haemophilic patients please don't be upset that u r haemophilic, but enjoy it. As god selected us to be haemophilic because only we had the courage to live with this abnormality & still come up with flying colours
#13 - sangarsh - 09/22/2011 - 04:01
sangarsh i really appreciate your views, i being an haemophilic know the pains of this disease, however since we have this we need to be strong enough to face it rather repent for the life. We must pray to God and live our life to the fullest with this ailment. I would just like to thank God and woul like my other friends to live their life just taking some precaution and without blaming others. My contact no is 9167309561
#14 - nchoudhary - 10/16/2011 - 14:19
my cousin sis suffering from haemophillia.plz tell me about latest treatment.
#15 - ekta ailawadi - 02/13/2012 - 05:08
My uncle was once a victim of hemophilia, Natural herbs help him greatly to get over it, I no more believe there is no cure to it. If you are victim of hemophilia, you can contact him, for advice and possible solution with this email: [email protected]
#16 - Jason - 12/06/2015 - 16:54
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