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Melanocytes

September 23, 2008

Melanocytes cells found in our body are responsible for producing melanin pigments. Melanin pigments are responsible for the color of our skin. The balanced or optimum melanin production is essential for proper skin pigmentation.

Sometimes the production of the pigment is disturbed due to various reasons. Such as, the impact of ultra violet radiations and hormonal activity disruption causes irregular melanin production. The group of melanocytes reduces melanin overall production due to which skin becomes dull and patchy.

Some melanocytes if stimulated, start excess production of melanin into the keratinocytes. Keratinocytes are the cells present in the epidermis. Keratinocytes are made up of darker pigments. These are forcibly moved to the surface of the skin due to cell renewal. This leads to the formation of age spots.

The skin undergoes changes that cause the appearance of blemishes at the age of 50’s or above 50’s. This is because the skin upper layer, epidermis loses half of its elasticity. This results in shifting of melanocytes containing, dark pigment to come near the skin surface and become visible as blemishes.

Besides this, the aging is associated with deceleration in cellular renewal. The communication between the keratinocytes and melanocytes rises and so the quantity of transmitted melanin also enhanced. Thus, the top layer of the skin becomes a thick cluster of highly pigmented cells.

It has been estimated by the dermatologists that 63% of age spots are the result of sun exposure and 13% is due to the age factor. It has also been found that 1 in 3 women suffer age spots over 40years of age and by 90% of women over 50 years of age.

Sometimes young women also suffer hyper pigmentation known as melasma. It is also known as “the mask of pregnancy” due to the response of the reactions to medicines or oral contraceptives used.


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