Gut Bacteria Fights Inflammatory Bowel Disease
August 21, 2008
It has been proved by a latest research that when any molecule generated from intestinal bacteria has the power of eradicating symptoms of IBD or inflammatory bowel disease, as experimented in mice.
IBD incorporates the form of ulcerative colitis and Crohn’s disease.
It has been proved earlier that the intestinal guts of mammals including humans involve almost one thousand variations of bacteria species that are helpful in fighting as well as preventing infection. These bacteria also aid in digestion. It is being anticipated that present elevation in number of asthmatic patients and many other kind of food allergies are a result of imbalance in the ecosystem of intestine.
Researches and studies have come across the fact that a molecule of sugar, i.e. polysaccharide is generated by a species of bacteria, i.e. Bacteroides fragilis in the intestine. It increases the number of cells of immune system, which exist as the protection against colitis and Crohn’s diseases.
The research associates at Harvard Medical School situated in Brigham and the California Institute of Technology prove the effect of immune-suppressed mice which are infected with bacteria, i.e. Helicobacter hepaticus.
Those mice showed distinct symptoms of IBD. Again they tested the mice after combining B. fragilis with H. hepaticus, found the mice did not develop any symptoms and remained healthy. Through further tests it was found that PSA generated by Bacteroides fragilis, which is a major matter in the prevention of IBD.
The PSA molecule stimulates immune cells to give off interleukin called IL-10, which is anti-inflammatory by nature. Thus, it is able to curb the inflammation taken place due to IBD.
It is for initial stage, a useful molecule generated by bacteria of intestine is proved to be curative in an experiment on the model of animal.
The researchers told that result of research clearly revealed the potential of “harmless” bacteria causing wellness in human health and so the patients suffering from the intestinal problems now need not worry.
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